Nature’s remedy: LPS, inflammation and non-pharmacological agents

floraEven with a long list of dentifrices, rinses, antibiotics and drugs to combat gingivitis and periodontitis, the battle continues. If you are in despair for what to prescribe next, don’t worry; there may be an answer from our botany-oriented colleagues. There is a growing wave of research being done that turns to nature to help fight our war against inflammation in the oral cavity. Many of these research projects focus on the main culprit of oral inflammation – the dreaded lipopolysaccharide (LPS). LPS is the byproduct of many periodontal pathogens, and it wreaks havoc on the supporting tissues comprising the periodontium. Researchers believe that if natural agents can mediate the inflammatory reaction of the host cells, then destruction of the gingiva and alveolar bone can be slowed or halted.